Safety guide

Beta-Carotene in Eye Supplements

Understand why beta-carotene was removed from AREDS2, what current and former smokers should know, and how this relates to VisiFlora's label.

For current and former smokers: beta-carotene is one of the few eye-supplement ingredients with a specific safety history that should not be glossed over.

Why beta-carotene appears in eye-nutrition discussions

Beta-carotene is a carotenoid and a precursor to vitamin A. The original AREDS formula used beta-carotene, but later evidence created concern about lung-cancer risk in smokers and former smokers.

What changed in AREDS2

AREDS2 replaced beta-carotene with lutein and zeaxanthin. National Eye Institute materials advise current and former smokers to avoid the older beta-carotene-containing AREDS formulation and use AREDS2 when an AREDS supplement is clinically appropriate.

What this means for VisiFlora

VisiFlora lists vitamin A as beta carotene at 450 mcg RAE. That amount is not the same as the old AREDS beta-carotene dose, so it would be inappropriate to claim the old AREDS risk applies identically. But the ingredient is present, which makes it worth discussing with a clinician if you currently smoke or smoked in the past.

Do not use this page to self-diagnose AMD

The decision to use AREDS2 is based on the stage of AMD seen on an eye examination. A supplement label cannot tell you whether you have intermediate AMD.